Crystal of recombinant interferon with altered spatial configuration, three-dimensional structure and uses thereof

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专利权人:

Sichuan Huiyang Life Science & Technology Corp.

发明人:

Guangwen Wei,Dacheng Wang

申请号：

US14461360

公开号：

US09273109B2

申请日:

2014.08.15

申请国别(地区):

US

年份:

2016

代理人:

摘要：

This invention provides crystalline recombinant interferon (rSIFN-co (SEQ ID NO: 1)) having (i) the same amino acid sequence as that of human consensus interferon, and (ii) altered three-dimensional structure as compared to IFN-α2b. The interferon of the present invention exhibits enhanced biological activities. The present invention also provides a structural model of said interferon useful for drug screening and/or drug design, and mimetics of said interferon.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/