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Combinations for the treatment of diseases involving cell proliferation
专利权人:
Gerd Munzert;Martin Steegmaier;Anke Baum
发明人:
Gerd Munzert,Martin Steegmaier,Anke Baum
申请号:
US12437280
公开号:
US08143247B2
申请日:
2009.05.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are pharmaceutical compositions for the treatment of diseases which involve cell proliferation. Also disclosed are methods for the treatment of said diseases, comprising co-administration of a compound 1 of Formula (I)wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given herein and of an effective amount of an active compound 2 and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of a compound 1 of Formula (I) and of an effective amount of an active compound 2 and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
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