An arm positioning device for supporting the arms of a patient in an arms-up position for some therapeutic or diagnostic procedure on the patient is disclosed. The device includes a base, a pair of wings or panels, and a pair of arm supports. The wings or panels extend upwardly and outwardly from the base and each mounts a respective one of the pair of arm supports thereon. The arm supports are configured to be slid along the wing or panel on which they are mounted to any one of plural working positions wherein they are located above the wing to hold the upper arm of a patient thereon. Each of the arm supports includes a cuff, which is pivotable to a retracted position located below the wing on which the arm support is mounted so as not to interfere with the placement of the patient on the arm positioning device.
