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COMMON LIGHT CHAINS AND METHODS OF USE
专利权人:
Hoffmann-La Roche Inc.
发明人:
Christian Klein,Ekkehard Moessner,Ralf Hosse,Peter Bruenker,Pablo Umana,Christiane Neumann
申请号:
US15600015
公开号:
US20170253670A1
申请日:
2017.05.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells comprising a common light chain. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
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