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DÉRIVÉ 6,7-INSATURATÉ-7-CARBAMOYL-MORPHINANE ET PROCÉDÉ POUR LE PRODUIRE
专利权人:
Shionogi & Co.; Ltd
发明人:
申请号:
EP19162034.3
公开号:
EP3560929A2
申请日:
2011.11.11
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to a process for preparing a compound of the formula (II):wherein R1b is a hydroxy-protecting group, R2 is optionally substituted lower alkyl, and R3 is optionally substituted lower alkyl, optionally substituted cycloalkyl, substituted or non-substituted aryl or substituted or non-substituted heteroaryl, characterized by reacting a compound of the formula (III):wherein R1b and R2 are the same as defined above, in the presence or absence of an acid with a compound of the formula: R3-N=C=O , wherein R3 is the same as defined above, or with a compound of the formula: R3-NH-C(=O)-X, wherein R3 is the same as defined above and X is a leaving group.
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中国工程科技知识中心
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