A wireless wearable device to detect inflammation may include motion sensors for generating motion signals in response to body motion (e.g., accelerometry), force sensors for generating force signals in response to force exerted by a body portion on the force sensor, and biometric sensors for generating biometric signals indicative of biometric activity in the body (e.g., arousal in the SNS). Processing of the force signals using the motion signals may be used to remove errors in the force signals caused by the body motion. The processing may generate a signal that indicates a state of the body that is an inflammation state (I), a contraction state (C) or a nominal state (N). The inflammation state may be attributed to systemic inflammation, the contraction state may be attributed to dehydration/severe dehydration, and the normal state may be attributed to a normal baseline tissue pressure in the body of a user.
