A tissue sample collection device and method are described and disclosed. The tissue sample collection device has a filter that is removably disposed within a sleeve. The filter has an open proximal end and an internal passageway that is in fluid communication with the open proximal end for the passage of fluids. The filter is substantially impermeable to tissue samples but allows the passage of fluids into the internal passageway at a plurality of spaced apart locations along at least a portion of the filters length. When used to collect tissue samples, the samples are collected on the exterior surface of the filter. Thus, the filter can be removed from the sleeve, and samples can be removed from the exterior surface of the filter. In certain exemplary versions of the tissue sample collection device, the filter is provided on a filter member, and the sleeve is adjustably attached to the filter to define a tissue collection configuration in which the filter is disposed within the sleeve and a tissue retrieval configuration in which filter projects away from the sleeve.
