Subhra Mohapatra,Shyam S. Mohapatra,Mahasweta Das,Chunyan Wang
申请号：
US13773718
公开号：
US20130230595A1
申请日:
2013.02.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided herein is a method of transfecting a brain cell of a subject with a polynucleotide comprising systemically administering to the subject a composition comprising a micelle having a hydrophobic superparamagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising the polynucleotide, wherein the subject has a mild traumatic brain injury.
