Described herein are methods for the treatment of an ophthalmic disease or disorder comprising the administration of non-retinoid visual cycle modulators. Ophthalmic diseases and disorders which can be treated according to the methods provided herein include age-related macular degeneration (AMD), Stargardt's disease, glaucoma, and other disorders that adversely affect the retina.La présente invention concerne des procédés de traitement d'une maladie ou d'un trouble ophtalmique comprenant l'administration de modulateurs non rétinoïdes du cycle visuel.