The invention relates to: - A resorbable crosslinked form stable membrane which comprises a composite layer of collagen material and inorganic ceramic particles containing 1.5 to 3.5 weight parts of inorganic ceramic for 1 weight part of collagen material, sandwiched between two layers of elastic pretensed collagen material, the collagen material comprising 50-100 % (w/w) collagen and 0-50 % (w/w) elastin, - the above crosslinked resorbable crosslinked form stable membrane for use as an implant to support bone formation, bone regeneration, bone repair and/or bone replacement at a non-containing dental bony defect site in a human or animal, - a process for preparing the above crosslinked resorbable crosslinked form stable membrane comprising the steps of: (a) Preparing a composite layer of inorganic ceramic particles and collagen material, optionally crosslinking that composite layer, (b) Assembling and glueing the composite layer of collagen material and inorganic ceramic particles between two layers of collagen material submitted to tensioning leading to a stretching of the collagen material in the linear region of the stress-strain curve, thereby giving a composite layer of collagen material and inorganic ceramic particles sandwiched between two layers of elastic pretensed collagen material , and (c) Crosslinking that composite layer of collagen material and inorganic ceramic particles sandwiched between two layers of elastic pretensed collagen material, followed by a hydrophilic making treatment.本發明係關於: -一種可再吸收的交聯形態穩定膜,其包含每1重量份膠原蛋白材料含有1.5重量份至3.5重量份無機陶瓷的膠原蛋白材料及無機陶瓷顆粒之複合層,該膠原蛋白材料及無機陶瓷顆粒之複合層夾在兩層彈性預拉緊膠原蛋白材料之間,該膠原蛋白材料包含50%至100% (w/w)之膠原蛋白及0%至50% (w/w)之彈性蛋白, - 該上述交聯型可再吸收的交聯形態穩定膜用作在人類或動物中之不含牙骨之缺損位點處支援骨骼形成、骨骼再生、骨骼修復及/或骨骼替換的植入物, - 一種用於製備該上述交聯型可再吸收的交聯形態穩定膜之方法,其包含以下步驟: (a) 製備無機陶瓷顆粒及膠原蛋白材料之複合層,視情況使該複合層交聯, (b) 在經受拉緊之兩層膠原蛋白材料之間裝配並膠合該膠原蛋白材料及無機陶瓷顆粒之複合層,該拉緊使得該膠原蛋白材料拉伸在該應力-應變曲線的線性區中;由此得到夾在兩層彈性預拉緊膠原蛋白材料之間的膠原蛋白材料及無機陶瓷顆粒之複合層,及 (c) 使夾在兩層彈性預拉緊膠原蛋白材料之間的該膠原蛋白材料及無機陶瓷
