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Methods of determining dosing of a therapeutic agent based on measured levels of a metabolite
专利权人:
Clear Creek Bio; Inc.
发明人:
KUMAR, Vikram S.,HESSON, David P.
申请号:
AU2019242626
公开号:
AU2019242626A1
申请日:
2019.03.26
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The invention provides methods of determining a therapeutically effective dose of an agent that targets a metabolic pathway based on measured levels of a metabolite in the pathway. The methods, which may include providing the agent in a therapeutically effective dose, are useful for treating disorders, such as cancer, in a subject. The invention also provides methods for assessing the impact of a therapeutic agent on a tumor in a subject by monitoring, in real time, metabolism of a molecule in the tumor, oxygenation of the tumor, or both. The invention further provides devices that determine a therapeutically effective dose of an agent that targets a metabolic pathway based on measured levels of a metabolite in the pathway and notify a subject to administer the dose.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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