Aspects of the invention include methods for applying to a subject a transdermal delivery device configured to deliver a non sedative amount of a dexmedetomidine composition. In practicing methods according to certain embodiments a non sedative amount of a dexmedetomidine composition is transdermally applied to a subject and is maintained in contact with the subject in a manner sufficient to deliver a non sedative amount of dexmedetomidine to a subject. Also provided are transdermal delivery devices having a non sedative amount of dexmedetomidine sufficient for practicing the subject methods as well as kits containing the transdermal delivery devices.
