[Problem] The present invention addresses the problem of providing an anti- Staphylococcus antibody having preventive or therapeutic effects on staphylococcal infections. [Solution] Provided is an anti -Staphylococcus antibody having preventive or therapeutic effects on staphylococcal infections and a method for manufacturing said antibody, as well as a composition, a product, and a drug containing said antibody. The antibody is obtained by using deacetylated Staphylococcus for immunization.