A single use syringe comprising a plunger arm, plunger tip, syringe body, and tip retaining sleeve is disclosed. The tip retaining sleeve surrounds tip retaining arms of the plunger arm allowing the tip retaining arms to grasp the plunger tip. When the plunger arm is pulled backwards, sleeve ribs of the tip retaining sleeve protrude into a sleeve lock of the syringe body and the tip retaining sleeve is prevented from moving in a forward direction. As the plunger arm is pushed forward, the tip retaining arms are no longer surrounded by the tip retaining sleeve and the tip retaining arms move outwards and release the plunger tip. After the plunger tip has been released from the plunger arm, the plunger tip and the plunger arm cannot be reconnected and the single use syringe cannot be reused.