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Methods of Treatment Using 3-Bromopyruvate and Other Selective Inhibitors of ATP Production
专利权人:
PRESCIENCE LABS; LLC
发明人:
Jean-Francois Geschwind,Mustafa Vali
申请号:
US13658696
公开号:
US20130046019A1
申请日:
2012.10.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides methods for preventing or treating infections, especially bacterial infections, by administering selective inhibitors of ATP production to inhibit glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase (GAPDH). As such, the present invention further provides methods for preventing or treating inflammation and sepsis associated with infections, as well as increased wound healing and decreased wound scarring.
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