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Use of ketogenic compounds for treatment of age-associated memory impairment
专利权人:
Samuel T. Henderson
发明人:
Samuel T. Henderson
申请号:
US12064850
公开号:
US08124589B2
申请日:
2007.04.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates to the field of therapeutic agents for the treatment of Age-Associated Memory Impairment (AAMI). In particular, the present invention utilizes compositions comprising at least one compound capable of elevating ketone body concentrations in a mammal (e.g., ketogenic compounds), administered in an amount effective for treatment or prevention of loss of cognitive function caused by reduced neuronal metabolism in AAMI. In one embodiment, the composition includes medium chain triglycerides (MCT). In another embodiment, the compositions are administered in the presence of carbohydrate. The present invention also relates to oral dosage forms, in particular, a nutritional drink comprising at least one compound capable of elevating ketone body concentrations in a mammal.
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