Efficient non-meiotic allele introgression

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专利权人:

Recombinetics; Inc.

发明人:

Scott C. Fahrenkrug,Daniel F. Carlson

申请号：

US14263446

公开号：

US09528124B2

申请日:

2014.04.28

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease system and a HDR template into a cell with a mismatch in the binding of the targeting endonuclease and the targeted site.

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