Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof

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专利权人:

田辺三菱製薬株式会社

发明人:

安藤 直子

申请号：

JP2010541324

公开号：

JP5357894B2

申请日:

2009.12.01

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

A compound represented by the formula (I) wherein R 1 and R 2 are each a hydrogen atom, an alkyl group and the like, R 3 is a hydrogen atom, an alkyl group and the like, R 4 is a hydrogen atom, an alkyl group and the like, m is an integer of 0 to 3, X is a bond, an oxygen atom or a sulfur atom, Y is a carbonyl group, a hydroxymethylene group and the like, and Z is a halogen atom, an alkyl group, an aryl group, a heteroaryl group and the like, or a pharmaceutically acceptable salt thereof has a superior PPAR± agonist action and a lipid-lowering action, and is useful as a prophylactic or therapeutic drug for hyperlipidemia and the like.

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