Methods to modulate Rac1 import and to treat pulmonary fibrosis

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专利权人:

University of Iowa Research Foundation

发明人:

Hohl, Raymond J.,Carter, A. Brent

申请号：

AU2014256956

公开号：

AU2014256956A1

申请日:

2014.04.25

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The invention provides methods for treating fibrosis, as well as methods for modulating mitochondrial peroxide production in a cell, and methods for modulating the import of Rac I into the mitochondria of a cell, comprising contacting the cell with an effective amount of a geranylgeranyl pyrophosphate (GGPP) synthase inhibitor or a pharmaceutically acceptable salt or prodrug thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/