Disclosed herein is the use of ibuprofen and paracetamol in the manufacture of a combination medicament for treating pain and/or inflammation in a human by intravenous administration, the medicament having: a) approximately 375 mg to approximately 425 mg ibuprofen, in combination with approximately 975 mg to approximately 1,025 mg paracetamol； or b) approximately 175 mg to approximately 225 mg ibuprofen, in combination with 475 mg to 525 mg paracetamol.
