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DUAL CHAMBER SYRINGE FOR MIXING AND DISPENSING ORAL LIQUID PHARMACEUTICAL DOSAGE FORMS DIRECTLY IN THE MOUTH OF A PATIENT
专利权人:
ZYWIE; LLC
发明人:
GILBERT, Eric S.
申请号:
USUS2016/023877
公开号:
WO2016/160469A1
申请日:
2016.03.24
申请国别(地区):
WO
年份:
2016
代理人:
摘要:
A dual chamber syringe for mixing and dispensing an oral liquid pharmaceutical dosage form comprising: (a) a syringe housing having an outer wall and a proximal and distal end portions, wherein the syringe housing comprises an upper chamber comprising a liquid containing pouch and a lower chamber comprising a dry component, wherein the liquid containing pouch comprises a liquid component (b) a piston positioned within the syringe housing and movable between the proximal and distal end portions of the syringe housing during use, wherein the piston provides an attachment means for securing the liquid containing pouch (c) a flow aperture at the distal end of the syringe housing for receiving and dispensing the oral liquid pharmaceutical dosage, wherein the oral liquid pharmaceutical dosage form comprises the liquid component and the dry component and (d) a puncture rod which is inserted into the syringe housing through the flow aperture to pierce the liquid containing pouch. Unexpected advantages of the dual chamber syringe for mixing and dispensing liquid oral pharmaceutical dosage forms include at least the following: (1) the dual chamber syringe is capable of storing two components which have to be mixed prior to use and does not affect the safety and quality of the oral liquid pharmaceutical dosage form (2) the dual chamber syringe is able to store formulations which are not stable for storage for a long time (3) the dual chamber syringe is simple and economical to manufacture and has a minimum number of parts to and (4) the dual chamber syringe is easy to use, and may be discarded after use.Linvention concerne une seringue à double chambre pour mélanger et distribuer une forme posologique pharmaceutique liquide à administration orale comprenant : (a) un corps de seringue ayant une paroi externe et une partie dextrémité proximale et une partie dextrémité distale, le corps de seringue comprenant une chambre supérieure comprenant une poche contenant un liquide et une
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中国工程科技知识中心
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