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METHOD FOR PREDICTION OF RISK OF SEVERE SECONDARY ANEMIA, REQUIRING BLOOD TRANSFUSION, IN YOUNG INFANTS UNDERGOING INTRAUTERINE BLOOD TRANSFUSION BECAUSE OF FETAL HEMOLYTIC DISEASE ON RHESUS FACTOR
专利权人:
Federalnoe gosudarstvennoe byudzhetnoe uchrezhdenie "Uralskij nauchno-issledovatelskij institut okhrany materinstva i mladenchestva" Minzdrava Rossijskoj Federatsii
发明人:
Ivanova Anastasiya Viktorovna,Zakharova Svetlana Yurevna
申请号:
RU20160128420
公开号:
RU2643338(C2)
申请日:
2016.07.12
申请国别(地区):
俄罗斯
年份:
2018
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention is a method for prediction of severe secondary anemia development, requiring blood transfusion, in young infants undergoing intrauterine transfusion (IUT) because of fetal hemolytic disease on the rhesus factor (HDN), which includes determination of the level of venous blood hematocrit at birth (A), determination of the average level of erythrocyte in venous blood on day 14-21 of life (A) calculation of the prognostic index (D) by the formula D=A×0.529-A×0.221+3.256 and prediction of a high risk of secondary anemia when D≥0, or prediction of the absence of secondary anemia when D<0.EFFECT: method allows to allocate a risk group in terms of severe anemia development at the out-patient stage, in the neonatality period children with fetal hemolytic disease on the rhesus factor after prenatal intrauterine blood transfusion, which gives an opportunity to prevent the development of this state and narrow the range of children, requiring frequent study of hemogram.2 ex
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