An angiographic injection system (10) comprising: an actuator a mounting chamber body (542) constructed and arranged to hold a syringe (500) a syringe (500) for insertion into the mounting chamber, said syringe including a barrel defining a pumping chamber (510), said syringe including a plunger (512) constructed and arranged within said pumping chamber for engagement with the actuator a motor (104) connected to said actuator to reciprocate the plunger (512) when engaged with the actuator a remote control (14) to generate a command signal wherein the motor speed is controlled by the command signal. The syringe (500) includes structure in form of plurality of frangible or breakable tabs (610) on its plunger support member (617) to ensure single use of the syringe (500).
