Prolexys Pharmaceuticals, Inc.;The Trustees of Columbia University in the City of New York;Whitehead Institute for Biomedical Research
发明人:
Qi, Longwu,Simmons, Keith,Robbins, Paul B.,Stockwell, Brent R.,Chepanoske, Cindy Lou,Sahasrabudhe, Sudhir R.,Venkat, Raj Gopal,Pelter, John M.,Selliah, Robert,Von Rechenberg, Moritz,Becklin, Robert R.
申请号:
AU2006208084
公开号:
AU2006208084B2
申请日:
2006.01.25
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention relates to methods of screening for binding partners, especially binding partners essential for the biological activity of erastin (e.g. VDACs such as VDAC3). The invention also provides reagents and methods for effective killing of cancer cells with erastin and related compounds or derivatives.