#$%^&*AU2014265070A120141211.pdf#####Abstract The invention relates to oligomeric compounds (oligomers), which target beta-catenin mRNA in a cell, leading to 5 reduced expression of beta-catenin. Reduction of betacatenin expression is beneficial for a range of medical disorders, such as hyperproliferative diseases, including cancer. The invention provides therapeutic compositions comprising oligomers and methods for modulating the io expression of beta-catenin using said oligomers, including methods of treatment. 59597301 (GHMatters) P82346.AU.1 PETERB 17/11/14