LIM, OK JAE,KIM, MUN KYUNG,LEE, YUN JUNG,LEE, JEE WON,YANG, WOO SEOK,KIM, YU YOUNG,KWON, YOUNG EUN,CHOE, SEUNG HYON
申请号：
CA3082331
公开号：
CA3082331A1
申请日:
2018.11.16
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to a transformed human cell and a use thereof and, more particularly, to a cell transformed with a gene for coding an MHC I cell membrane receptor and an MHC II cell membrane receptor by using a gene expression suppressing system using a guide RNA, and a use thereof. Such a transformed cell can effectively exhibit the therapeutic effect of cells even in vivo, and cannot be removed by an in vivo immune response. Therefore, it is expected that a composition comprising the immunocyte as an active ingredient can be usefully used for the treatment of cancer, infectious diseases, degenerative diseases or immunological diseases.
