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MEANS FOR INVOLVING PLURIPOTENT STEM CELL ORIGINING FROM THE BONE MARROW IN THE PERIPHERAL BLOOD
专利权人:
ОСАКА ЮНИВЕРСИТИ (JP);ДЖЕНОМИКС КО.;ДЖЕНОМИКС КО., ЛТД. (JP); ЛТД. (JP)
发明人:
ТАМАИ Кацуто (JP),ЯМАЗАКИ Такехико (JP),ТИНО Такенао (JP),КАНЕДА Ясуфуми (JP)
申请号:
RU2010148792/15
公开号:
RU2010148792A
申请日:
2009.04.30
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A tool for involving bone marrow cells in peripheral blood from bone marrow, which is injected into a blood vessel or muscle and which contains any of the components:! (a) HMGB1 protein; ! (b) a cell that secrets the HMGB1 protein; ! (c) a vector into which DNA encoding the HMGB1 protein is inserted; ! (d) HMGB2 protein; ! (e) a cell that secrets the HMGB2 protein; ! (f) a vector into which DNA encoding an HMGB2 protein is inserted; ! (g) an HMGB3 protein; ! (h) a cell that secrets the HMGB3 protein; and! (i) a vector into which DNA encoding an HMGB3 protein is inserted. ! 2. A tool for involving bone marrow cells in peripheral blood from bone marrow, which is obtained by a method comprising the step of immersing a cell or tissue in a solvent, and which is injected into a blood vessel or muscle. ! 3. A tool for involving bone marrow cells in peripheral blood from bone marrow, which is injected into a blood vessel or muscle and which contains a heparin-binding fraction obtained by a method involving steps! (a) immersing the cell or tissue in a solvent; ! (b) contacting the immobilized heparin with the extract obtained in stage (a); and! (c) eluting the heparin binding fraction from immobilized heparin. ! 4. A method for evaluating whether a factor that draws a bone marrow cell into peripheral blood from bone marrow is contained in a cell or tissue extract, and when the activity of involving a bone marrow cell into peripheral blood from bone marrow in stage (b) exceeds the control activity determining that the factor is contained in an extract of a cell or tissue, where the method comprises the steps indicated below:! (a) obtaining a cell extract; and! (b) measured1. Средство для вовлечения клетки костного мозга в периферическую кровь из костного мозга, которое вводят в кровеносный сосуд или мышцу и которое содержит любой из компонентов: ! (a) белок HMGB1; ! (b) клетка, которая секретирует белок HMGB1; ! (c) вектор, в который встроена ДНК, кодирующая белок HMGB1
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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