Pharmaceutical compositions and dermatological compositions comprising a prebiotic chosen among gluco-oligosaccharides (GOS), fructo-oligosaccharides (FOS), galacto-oligosaccharides and mixtures thereof; and a plant extract containing isoflavones chosen among soybean (Glycine max) extracts, clover (Trifolium sp.) extracts and mixtures thereof. Uses for the treatment of bacterial vaginoses and/or the treatment of vaginal mucosae that aim to promote the development and growth of a beneficial vaginal microflora.