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Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
专利权人:
Pierre-Francois Tosi
发明人:
Pierre-Francois Tosi,Claudie Madoulet,Claude Nicolau,David T. Hickman
申请号:
US12870893
公开号:
US08409580B2
申请日:
2010.08.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies.The invention relates to said composition for defining means for treating multidrug resistances.
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