The present invention relates to transferrin, possibly in combination with an iron-chelator (e.g. deferoxamine) or a PHD2 enzyme inhibitor, for use in the treatment of Hypoxia Inducible Factor (HIF)-related conditions, in particular associated with organ transplantation, ischemia, oxygen deprivation, interruption of blood during surgical intervention, or neurodegenerative disorders.COMPOSICIÓN QUE SIRVE PARA PREPARAR UN MEDICAMENTO ÚTIL PARA TRATAR ENFERMEDADES RELACIONADAS CON EL FACTOR INDUCIBLE POR HIPOXIA (HIF).