An endoscope apparatus includes an endoscope including an insertion portion which is insertable into a living body an illumination section which emits illumination light to an observation target region side in the living body a light amount control section which performs light amount control to at least decrease an amount of light in a red wavelength range in the illumination light which excites a photosensitizing substance which is administered to the observation target region and a signal processing section which, in response to the light amount control, performs signal processing to increase a luminance level of a red color signal that corresponds to a red wavelength range in picking up an image under the illumination light.