A multi-sensor wireless abdominal monitoring system comprising a low-profile belt that fits around the abdomen and is embedded with specialized wireless sensors. The system is configured to continuously monitor a range of gastrointestinal and abdominal wall functions. The system wirelessly transmits data to an external device, such as a smartphone or computer for storage and download to a central server. The acquired data may be monitored remotely through specialized software that generates clinically interpretable information presented through a graphical user interface. The device provides data that are immediately actionable for a wide range of inpatients and outpatients with high prevalence disorders in varied clinical settings.