The present invention refers to a tubing set (12) suitable for use in co-operation with a medical liquid delivery device (10). The tubing set comprises: a delivery tube (68) suitable for supplying a medical liquid or blood to a patient; and a vial gate (24) for the connection of vials (26) containing drugs to be delivered into the medical liquid or blood. The vial gate comprises a delivery lumen (28), suitable for delivering the drug (30) from the vial to the delivery tube; and a vent lumen (32), suitable for providing a replacement fluid (34, 60) from a location (20, 64) inside the tubing set (12) to the inside of the vial in order to replace the delivered drug. The vial gate according to the invention further comprises at least one one-way valve (70, 72) placed along said vent lumen or said delivery lumen.本發明係有關於一種適用於與一醫療用輸液裝置(10)合作之導管線(12)。該導管組包括:一輸送管(68),適用於供應醫療用液體或血液給病人;以及一藥瓶閘門(24),用於連接容納欲被輸送至該醫療用液體或血液中之藥物的藥瓶(26)。該藥瓶閘門包括一輸送內腔(28),其適用於從該藥瓶輸送藥物(30)至該輸送管(68);以及一通氣內腔(32),其適用於從在該導管組(12)內之位置(20、64)提供一替換流體(34、60)至該藥瓶之內部,以便替換該被輸送藥物。依據本發明之藥瓶閘門進一步包括沿著該通氣內腔或該輸送內腔設置之至少一單向閥(70、72)。