The present invention relates to the field of radiation therapy and radiation surgery. In particular, the invention relates to devices and methods for stereotactic medical procedures and it provides for repeated accurate positioning (fixation) of a patient, or a part of a patient, for carrying out medical procedures which are done at different times such as fractionated radiation therapy. Specifically, a patient fixation device for fixating a head of a patient relatively a treatment unit as a preparation for treatment or during treatment of the head is provided. The patient fixation device being is adapted to be attached to a stereotactic frame structure connected to the treatment unit. The attachment means is adapted to be releasably attached to corresponding attachment plates attached to teeth of the upper jaw or maxilla of the patient, each attachment plate being fixated to at least one tooth by means of an adhesive, wherein the attachment means allows removal from the attachment plates of the patient and re-attachment to the corresponding attachment plates of the patient with an identical orientation relatively the frame structure and the teeth of the patient.