BIGNER, Darell D.,GROMEIER, Matthias,DESJARDINS, Annick,FRIEDMAN, Henry S.,FRIEDMAN, Allan H.,SAMPSON, John H.
申请号:
EP17770887
公开号:
EP3432901A4
申请日:
2017.03.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. Sequential treatment with the virus construct followed by chemotherapy drugs increases the anti-tumor effect. Tumors of different types are susceptible to the combination treatment, including but not limited to melanoma, glioblastoma, renal cell carcinoma, prostate cancer, breast cancer, lung cancer, medulloblastoma, and colorectal cancer.