PROCESS FOR PREPARATION OF ATOVAQUONE AND NOVEL INTERMEDIATES THEREOF

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专利权人:

发明人:

KUMAR ASHOK,DIKE SUNEEL YESHWANT,MATHUR PRAMIL KUMAR,KORE SWAPNIL SHREEKANT,BUCHUDE VITTHAL SURYABHAN

申请号：

IN760/MUM/2007

公开号：

IN251515B

申请日:

2007.04.19

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

Disclosed herein is novel process of Atovaquone, which process includes reacting 1,4-naphthoquione with trans-4-(4-chlorophenyl) cyclohexane carboxyane carboxylic acid followed by halogenation to obtain dihalo-compound, further dehydrohalogenation of dihalo-compound to obtain monohalogeno-compound, and hydrolysis of the monolageno-compound to obtain Atovquone.

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