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COMPOSITIONS AND METHODS FOR MODELING HEART FAILURE WITH PRESERVED EJECTION FRACTION
专利权人:
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
Joseph A HILL,Gabriele G SCHIATTARELLA,Thomas G GILLETTE
申请号:
US16309026
公开号:
US20190307107A1
申请日:
2017.06.12
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Aspects of the disclosure relate to a composition comprising 20-60% w/w of fat combined with a nitric oxide synthase inhibitor. Method aspects of the disclosure relate to a method for inducing heart failure with preserved ejection fraction in an experimental laboratory animal, the method comprising administering a composition of the disclosure or a composition comprising 10-60% w/w of fat and a composition comprising a nitric oxide synthase inhibitor to the laboratory animal.
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