An application of a radiofrequency catheter ablation system to treatment of essential hypertension. The treatment process is under ultrasonic guidance, an electrode needle is made to penetrate into target tissue of a patient, electrification is conducted to start ablation, the needle is withdrawn or made to penetrate into the other side of the target tissue for target ablation after reaching ablation temperature and duration time, and overall ablation treatment is completed. The system can treat a secondary center for regulating the activity of a whole-body sympathetic system to reduce its activity, thus, the blood pressure level of a patient can be reduced, and fewer kinds and smaller dosage of antihypertensive drugs taken or ceased altogether. By treating the secondary center, the activity of the whole-body sympathetic system, insulin resistance and whole-body fibrosis is reduced, and other diseases characterized in activity abnormity of the sympathetic system might be treated too.
