Robert Shoemaker,John Cardellina,Michael Currens,Sudhir Kondapaka,Yves Pommier,Andy Jobson,Dominic Scudiero,David Waugh,George Lountos,Charles M. Cook,Guangtao Zhang,Andrew Colasanti,Christopher R. Se
申请号：
US12135575
公开号：
US08765802B2
申请日:
2008.06.09
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided herein are Compounds having the following structure:wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.
