Carlo Scolastico,Leonardo Pierpaolo Manzoni,Pierfausto Seneci,Laura Belvisi,Domenico Delia,Martino Bolognesi,Eloise Mastrangelo,Mario De Mayo De Mari Milani,Ilaria Motto,Carmelo Drago
申请号：
US12741862
公开号：
US08609685B2
申请日:
2008.11.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to compounds conformationally constrained mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients.
