ЛУТРИНГЕР Реми Анри (CH),ПЕЛЛЕГРИНИ Лоренцо (US),КАРАБЕЛАС Аргерис Н. (US)
申请号：
RU2013107382/13
公开号：
RU2013107382A
申请日:
2011.07.20
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A method for treating or improving at least one disorder parameter or sleep in a subject, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula I or a pharmaceutically acceptable salt, hydrate or solvate thereof, wherein: X represents an alkyl group , cycloalkyl-substituted alkyl group-substituted alkyl group-substituted alkenyl group, aromatic-substituted alkynyl group, a monocyclic or polycyclic cycloalkyl group which may be for meschena alkyl group, an aryl group, a heterocyclic group, or a substituted or unsubstituted amino group Q represents a group having --SO--, --O--, --S--, --CH (OR) -, - -C (= CH) - or --With (= NR) -, wherein R is a hydrogen atom, an alkyl group, a hydroxyalkyl group or an acyl group, and R is a hydroxyl group, an alkoxyl group, an aralkyloxy group, an acyloxy group, an acylamino or alkoxycarbonylamino group n is an integer from 0 to 5 each independently represent a hydrogen atom or an al yl group B represents the following groups: wherein R, R, each independently represent a substituent selected from the group consisting of a hydrogen atom, a halogen atom, a nitro group, an alkyl group, a halogenated alkyl group, a hydroxyl group, an alkoxyl group, a halogenated alkoxyl group and a cyano group m represents 1 or 2.2. A method according to claim 1, wherein the subject does not suffer from shizofrenii.3. A method according to claim 2, wherein the subject suffers from shizofrenii.4. A method of treating or alleviating at least one SIM
