The invention relates to a method for the treatment of brain metastases from non-small cell lung cancer in a subject, comprising administering to the subject an effective amount of 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide, or a pharmaceutically acceptable salt thereof, in combination with an effective amount of whole brain radiation.本發明係關於一種治療個體非小細胞肺癌腦轉移之方法,該方法包括投與該個體有效量之2-[(2R)-2-甲基吡咯啶-2-基]-1H-苯並咪唑-4-羧醯胺或其醫藥可接受鹽與有效量全腦放射併用。