#$%^&*AU2016203312A120160609.pdf#####dATRACT The invention relates to novei chemical compounds. compositions and methods of making and using the same in particular the invention provides pyridazine compounds and/or related hete rocydlic derivatives. composlitions comprising the same, and methods of making ad using pyridazine compounds and/or related heterocyclic derivatives and composions composing the same, for modulation of cellular pathways (e~g signal transduction pathways), for treatment or prevention of inflammatory diseases (eg Alzhmer disease) for research, drg screening, and therpeud applations.
