GIFFERS, Christian,HILL, Oliver,THIEMANN, Meinolf,BRANSCHADEL, Marcus
申请号:
AU2017201232
公开号:
AU2017201232B2
申请日:
2017.02.23
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2017201232B220180322.pdf#####TNF SUPERFAMILY COLLECTIN FUSION PROTEINS ABSTRACT The present invention refers to a fusion protein comprising a TNF- superfamily (TNFSF) cytokine or a receptor binding thereof fused a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications.