Bruce Keyt,Lawrence M. Kauvar,Ellen J. Collarini,Orit Foord,Gizette Sperinde,Marjan Fatholahi,Hung Nguyen
申请号:
US14475348
公开号:
US09321839B2
申请日:
2014.09.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Recombinant materials and methods for producing antibodies that specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer that expresses HER3.