SATO, Shuji,BEAUSOLEIL, Sean, Andre,CHEUNG, Wan, Cheung,POLAKIEWICZ, Roberto, D.
申请号:
USUS2013/038814
公开号:
WO2013/165982A3
申请日:
2013.04.30
申请国别(地区):
WO
年份:
2014
代理人:
摘要:
This disclosure provides anti-human cytomegalovirus antibodies and methods of treatment, prophylaxis, detection, and diagnosis using the same. In another aspect, the disclosure features therapeutic, prophylactic, and/or diagnostic compositions for human cytomegalovirus infection or for a human cytomegalovirus-related disease that include a binding agent (e.g., antibody) or polynucleotide disclosed herein. In some embodiments, the composition is formulated for ocular or topical administration. The compositions can further include one or more human cytomegalovirus-neutralizing antibodies, an intravenous immunoglobulin preparation, and/or one or more antiviral compounds (e.g., ganciclovir, foscamet, cidofovir, or valganciclovir).Cette invention concerne des anticorps anti-cytomégalovirus humain et des méthodes de traitement, de prophylaxie, de détection et de diagnostic à laide de ceux-ci.