Modified pigment epithelium-derived factor (PEDF) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, cancer, and for cytoprotection
Northwestern University;Board of Regents of the University of Nebraska
发明人:
Jack Henkin,Olga Volpert,Serguei Vinogradov,Ignacio Melgar-Asensio
申请号：
US15497822
公开号：
US10081668B2
申请日:
2017.04.26
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are modified pigment epithelium-derived factor (PEDF) peptides, particulate carrier prodrugs thereof, and pharmaceutical compositions comprising the peptides or particulate carrier prodrugs. The peptides, particulate carrier prodrugs, and pharmaceutical compositions may be used to treat diseases and disorders that are amenable to treatment with anti-angiogenic agents, anti-tumorigenic agents, anti-fibrotic agents, chemotherapy-protecting agents, and immune stimulating agents.
