CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人:
BENKIRANE, MONSEF,LAGUETTE, NADINE,SOBHIAN, BIJAN
申请号：
EP12711154.0
公开号：
EP2688574A1
申请日:
2012.03.23
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The present invention relates to an in vitro method of screening for candidate compounds capable of being used for the preventative and/or curative treatment of a disease caused by a retrovirus in which the candidate compound which modulates the expression and/or the activity of the SAMHD1 protein is identified as a candidate compound capable of being used for the preventative and/or curative treatment of a disease caused by a retrovirus. The invention also relates to a vaccine composition and an immunogenic composition, comprising i) an inhibitor of the expression and/or of the activity of the SAMHD1 protein and ii) at least one antigen of a retrovirus.
