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Procedures for administration of an EGFR inhibitor
- 专利权人:
- Boehringer Ingelheim International GmbH
- 发明人:
- LORENCE, Robert Michael,SHAHIDI, Mehdi,STOPFER, Peter
- 申请号：
- ES11752700
- 公开号：
- ES2655115T3
- 申请日:
- 2011.08.24
- 申请国别(地区):
- ES
- 年份:
- 2018
- 代理人:
- 摘要：
- A pharmaceutical composition comprising BIBW 2992 or a pharmaceutically acceptable salt thereof, for use in a procedure for the treatment of a patient with non-small cell lung cancer (NSCLC) by a method comprising a) identifying a patient in need. treatment with BIBW 2992 or a pharmaceutically acceptable salt thereof； b) determine that the patient is receiving therapy with a P-gp inhibitor selected from alfentanil, amiloride, amiodarone, amitriptyline, astemizole, atovaquone, atorvastatin, azelastine, azidopine, azithromycin, bepridil, biricodar, bromocriptine, carbamazepine, carbamazepine, carbamazepine, carbamazepine, carbamazepine, carbamazepine, carbamazepine, carbamazepine chlorpromazine, clarithromycin, cyclosporin, cyproheptadine, darunavir, desethylamiodarone, desipramine, dexniguldipina, dexrazoxane, diltiazem, dipyridamole, disulfiram, doxazosin, elacridar, emetine, erythromycin, felodipine, fenofibrate, fentanyl, flavonoids, fluoxetine, fluphenazine, fluvoxamine, fucidina, gallopamilo, glyburide, gramicidin D, grapefruit juice, garlic, green tea, haloperidol, hydrocortisone, hydroxyzine, josamycin, ketoconazole, imipramine, itraconazole, ivermectin, ketoconazole, laniquidar, lansoprazole, levothyroxine, lidocaine, loperamide, lopinavir, loratadine, lovastatin, maprotiline, mefloquine, methadone, mibefradil, midazolam, mitomycin C, nefazodone, nelfinavir, nicardi pineapple, nitrendipine, nobiletin, norverapamil, omeprazole, orange juice, ofloxacin, paroxetine, pantoprazole, phenothiazines, phenobarbital, piperine, pimozide, probenecid, progesterone, promethazine, propafenone, propranolol, quercetin, quinacrine, quinina, quinoline saquinavir, sertraline, simvastatin, spironolactone, sufentanil, tacrolimus, tamoxifen, tariquidar, telithromycin, terfenadine, testosterone, tetrabenazine, thioridazine, trifluoperazine, trifluopromazine, trimipramine, valinomycin, vanadate, venlafaxine, verapamil, vinblastine, FK506, RU486 (mifepristone), valspodar PSC 833, zosu
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
