Donald J. Buchsbaum,Albert F. Lobuglio,Tong Zhou,Kimberly Foreman
申请号：
US13634401
公开号：
US20130004521A1
申请日:
2011.03.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is a method of determining the level of resistance or sensitivity of cancer stem cells to a death receptor agonist. The method includes detecting the level of IAP in one or more DR5/DDX3/IAP complexes in or from the cancer stem cells. Also provided is a method of killing cancer stem cells in a subject and a method of reducing the risk of cancer recurrence in a subject.
